CDSCO Warns Against Painkiller, Antibiotic Misuse Over Kidney and AMR Risks

CDSCO Warns Against Painkiller, Antibiotic Misuse Over Kidney and AMR Risks

The Central Drugs Standard Control Organisation (CDSCO) has issued an advisory urging doctors, pharmacists and the public to avoid indiscriminate use of painkillers and antibiotics, citing risks including kidney damage, adverse drug reactions and antimicrobial resistance.

In its September 21 circular, the drug regulator said non-steroidal anti-inflammatory drugs (NSAIDs) and antibiotics should be used only when clinically indicated, at the appropriate dose and for the prescribed duration under medical supervision. Most NSAIDs fall under Schedule H, while most antibiotics are listed under Schedule H1 and require a registered medical practitioner's prescription.

The CDSCO warned that repeated or prolonged NSAID use can affect kidney function, particularly among people with existing kidney disease, dehydration or cardiovascular conditions. Doctors have been advised to consider patients' age, medical conditions and other medicines before prescribing these drugs and to use the lowest effective dose for the shortest appropriate duration.

The regulator also cautioned against taking antibiotics without medical advice, especially for viral infections where they provide no benefit. Unnecessary antibiotic use can contribute to antimicrobial resistance, making bacterial infections increasingly difficult to treat.

Patients have been advised to complete prescribed antibiotic courses as directed, without sharing medicines or using leftovers. Pharmacists and retailers have also been instructed to follow prescription requirements, while hospitals and state drug authorities have been asked to strengthen prescription monitoring, patient counselling and antimicrobial stewardship.

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